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KMID : 0882420130850030329
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Korean Journal of Medicine
2013 Volume.85 No. 3 p.329 ~ p.333
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A Case of Thymoma with Immunodeficiency (Good’s Syndrome) with Disseminated Tuberculosis
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Jung Hyeon
Sohn Kyung-Mok
Kim Yeon-Sook
Song Chang-Hun
Sohn Eun-Hee
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Abstract
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Good’s syndrome is the rare association of immunodeficiency with thymoma, characterized by hypogammaglobulinemia, depleted B-cells, diminished T-cells and inversion of the CD4/CD8 ratio. Thymectomy does not usually improve hypogammaglobulinemia; thus, the patient remains prone to infections. Infections affect primarily the sinopulmonary and gastrointestinal system. Here we present a case of a 71-year-old woman with common manifestations of Good’s syndrome who succumbed to disseminated tuberculosis. Serum immunoglobulin levels should be measured for patients with thymoma and susceptibility to infection.
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KEYWORD
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Immunologic deficiency syndromes, Thymoma, Tuberculosis, Opportunistic infections
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